73-year-old woman presents with hematuria and ARF. Serum
creatinine is 10.2 mg/dl. BP
160/62. P-ANCA positive. She gives
history of hemoptysis in 2005. What will
the renal biopsy show?
ANCA+ with anti-myeloperoxidase titers:
6/14/05 26 units
8/17/05 5.4
units
10/18/05 1.3 units
12/13/05 <1.0
units
11/07/06 1.3 units
05/08/07 2.3 units
08/14/07 16 units
11/25/08 155 units
02/10/09 26 units
05/15/09 15 units two days after the biopsy
Pauci-immune crescentic glomerulonephritis; in this setting, most likely MPA.
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