Monday, July 9, 2012

ELECTROLYTE QUIZ

A 58-year-old male in the intensive care unit is intubated for respiratory failure due to severe pneumonia and is paralyzed with vecuronium and sedated with lorazepam. A renal consult is called because of the laboratory finding of metabolic acidosis.

Laboratory Studies
Serum sodium 136 mEq/L
Serum potassium 4.0 mEq/L
Serum chloride 101 mEq/L
Serum bicarbonate 14 mEq/L
Blood urea nitrogen 13 mg/dL
Serum creatinine 0.8 mg/dL
Serum glucose 108 mg/dL
Serum lactate 10 mmol/L
Serum osmolality 299 mOsm/kg
Arterial blood studies on 60% O2:
pH 7.37
PCO2 20 mm Hg

The most appropriate next step in the management of this patient is:
A. Dopamine
B. Dobutamine
C. Abdominal computed tomography
D. Discontinue lorazepam
E. None of the above 

2 comments:

  1. The patient has AGAP metabolic acidosis with positive osmolal GAP. In this setting, most likely from propylene glycol toxicity in patient receiving high-dose lorazepam.
    I would discontinue Lorazepam.

    ReplyDelete